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Vytrus Biotech has reported quantifying Phyto-PDRN and ExoPDRN in its hair-care actives, extending its plant-based PDRN portfolio across skin, scalp and hair. The company cites clinical, ex vivo and comparative testing for individual products, but the supplied report does not provide study sizes, methods or full results.
Vytrus Biotech says it has quantified two forms of plant-derived PDRN in its hair-care actives, extending its reported portfolio of ingredients and product applications across skin, scalp and hair. The company also describes study findings for hair density, scalp redness and curly-hair performance, though the information provided does not include study sizes or detailed methods.
Vytrus describes its approach as using PDRN naturally present in plant stem-cell actives in two forms. Phyto-PDRN consists of DNA fragments that, according to the company, act at the cell surface; ExoPDRN is PDRN naturally encapsulated within plant exosomes. Vytrus characterizes the combination as a dual-action approach operating at the cell surface and inside the cell. The company says it has now quantified both forms in its hair-care actives for the first time.
For Capilia Longa, an active derived from Curcuma longa stem cells, Vytrus reports clinical evidence of reduced hair loss and increased hair density. The company says scientific literature linking PDRN with hair growth is consistent with those findings. The source does not provide the clinical trial design, participant numbers, effect sizes or the length of the study, so the reported outcomes cannot be assessed in detail from the available information.
For Elaya Renova, made from Mediterranean olive stem cells, Vytrus says ExoPDRN reduced scalp redness compared with placebo. It also reports a new ex vivo curly-hair study: one leave-on application improved hydration, reduced combing effort and frizz in high humidity, and increased curl definition. These are company-reported results; the source does not give numerical measurements or explain how long the effects lasted.
A Broader PDRN Portfolio for Hair
The report shows how Vytrus is positioning plant-derived PDRN beyond skin care and toward hair density, scalp comfort and curl care. For cosmetic formulators, the company is presenting a set of plant-origin actives for different product needs rather than a single ingredient with one advertised use. That could widen the options available to brands seeking plant-based ingredients, while leaving questions about comparative performance and independent validation for buyers to examine.
The claims also matter to consumers because they concern outcomes that can be difficult to judge from ingredient descriptions alone. Hair loss, scalp redness and frizz are distinct concerns, and evidence for one product or outcome does not establish that all PDRN products will have similar effects. Vytrus’s report offers specific study descriptions, but without protocols and quantitative results readers cannot determine the size or practical significance of the reported changes.
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From Skin Studies to Hair Actives
The hair-care findings follow plant-based PDRN skin-care studies that Vytrus says it presented in April. Its Centella Reversa combines Phyto-PDRN and ExoPDRN in a secretome, which the company associates with skin rejuvenation, regeneration and cellular DNA protection. Sensia Carota contains Phyto-PDRN and is described as intended to calm and protect sensitive skin, with the company reporting reduced redness.
With the new hair-care information, Vytrus says its portfolio now spans skin, scalp and hair, including skin-soothing and regeneration products, hair-loss prevention and redensification claims, curl-care applications and scalp comfort. The source is a company-focused report and does not compare these actives with other ingredients or establish that the products are treatments for medical conditions.
““a dual-action strategy””
— Vytrus Biotech, describing its PDRN approach
Study Methods and Results Still Missing
The supplied report does not state the sample sizes, study durations, protocols or numerical effect sizes for the hair and scalp findings. It also does not identify the clinical study behind the Capilia Longa claim or provide enough detail to assess how the placebo comparison for Elaya Renova was conducted. The curly-hair findings are described as ex vivo, which means the source does not establish that the same outcomes occur in everyday use by consumers.
It is also unclear whether the reported effects persist with repeated use, how the products perform across different hair types or scalp conditions, and whether independent researchers have replicated the findings. The company’s language about hair loss and skin benefits should not be taken as evidence that these cosmetic products diagnose or treat medical conditions.
More Evidence Needed for Evaluation
Vytrus says formulators can contact the company for further information about its plant-based PDRN ingredients. The next useful step for evaluating the report would be publication or provision of the underlying study details, including methods, participant numbers where applicable, measurements and results. That information would help brands and readers distinguish between laboratory or ex vivo observations and effects demonstrated in routine consumer use.
Until more detail is available, the reported findings remain company-described evidence about specific actives and tests. No launch dates, additional trials or independent assessments are specified in the supplied material.
Key Questions
What does Vytrus mean by plant-based PDRN?
Vytrus describes Phyto-PDRN as DNA fragments that act at the cell surface and ExoPDRN as PDRN naturally encapsulated in plant exosomes. The company says both occur in its plant stem-cell actives.
What hair-care findings did Vytrus report?
The company says Capilia Longa was associated with reduced hair loss and increased hair density in clinical evidence. It also reports reduced scalp redness versus placebo for Elaya Renova, plus ex vivo findings on hydration, combing effort, frizz and curl definition.
Are the results independently confirmed?
The supplied report attributes the findings to Vytrus and does not describe independent replication. It also omits key study details, including sample sizes and numerical results.
Does this mean plant PDRN products treat hair loss?
No such conclusion is established by the supplied information. The report describes cosmetic product claims and company-reported studies; it does not establish that these products are medical treatments for hair loss or other conditions.
Source: cosmeticsbusiness.com
